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Best-in-Class Handling, Enhanced with Collagen

Agilon Moldable bone grafting product is the latest moldable grafting solution in Biogennix’ advanced bone graft product line.  Developed with Biogennix proprietary TrelCor technology, Agilon Moldable consists of a suspension of 1-2mm TrelCor granules in a rapidly absorbing, organic binder blended with type-1 collagen.

TrelCor granules provide enhanced bone formation due to the combination of a nanocrystalline surface with an HCA composition and interconnected pore structure that emulate human cancellous bone.  The added collagen fibers in Agilon Moldable increase the overall cohesiveness, providing a firmer and more cohesive feel without sacrificing moldability. Additionally, the added collagen minimizes residual material left on surgical gloves, aiding in optimal handling characteristics during intraoperative placement. The organic binder resists breakdown during handling and placement, then is rapidly absorbed, leaving behind the porous TrelCor granules, which are resorbed, remodeled, and replaced with bone over the next 6-12 months.

Configuration: Moldable

Chemistry: Nanocrystalline hydroxycarbanoapatite (HCA) / calcium carbonate (CC) granules and type 1 bovine collagen in an organic binder

Architecture: Biomimetic structure similar to cancellous bone; interconnected porosity

Granule Pore Size: 500 microns (µm)

Binder Absorption Profile: 1-2 days

Storage and Handling: Room temperature, no reconstitution or rehydration required

Configuration: Putty

Chemistry: Calcium phosphate (CP)/calcium carbonate (CC) granules and type 1 bovine collagen in an organic binder

Architecture: Biomimetic structure similar to cancellous bone; interconnected porosity

Granule Pore Size: 500 microns (µm)

Binder Absorption Profile: 1-2 days

Storage and Handling: Room temperature, no reconstitution or rehydration required

Agilon DIFFERENCE

Unlike other porous ceramic materials, Agilon Moldable provides the surgeon an advanced bone graft that is actively involved in the bone healing process

TrelCor Technology

  • Nanocrystalline structure provides an optimal surface for cell attachment and bone regeneration
  • HCA composition closely mimics human bone mineral and provides an enhanced osteoconductive surface
  • Biomimetic pore structure similar to cancellous bone allows for bone in-growth throughout the implant, and results in a robust scaffold that resists crushing during intraoperative handling

Best-in-Class Handling, Enhanced with Collagen

  • Firm consistency is moldable, cohesive, and mixable with autograft
  • Stays in place, holds its shape, and resists irrigation
  • Leaves minimal residue on gloves
  • No hydration required
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